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Blood Cancer (Leukemia) Treatment in Germany

photo of cancer cells

Blood cancer (leukemia) accounts for about 8% of all cancer pathologies. This disease is among the leaders in malignant neoplasms. The outdated term blood cancer today refers to several different pathologies in which the hematopoietic system and lymphoid tissue suffer. Depending on which of them undergoes abnormal changes and how the pathological process proceeds, approaches to blood cancer therapy in hematological centers of different countries also differ. The effectiveness and cost of treatment also vary.

Problem

Malignant tumors of the hematopoietic and lymphoid tissue affect people of different age groups, but children and people over 50 are especially often faced with this problem.

The disease can develop slowly, practically without showing itself. In acute course, the disease is very aggressive and can literally take a person's life within a few months. That is why treatment must be started as soon as possible after diagnosis.

Detection of the disease at an early stage and timely start of treatment gives a good result and allows complete cure or transfer of the pathology into long remission.

Oncohematological diseases (outdated — leukemia, blood cancer) often occur spontaneously, and doctors cannot establish their exact cause. It is believed that the risk of leukemia increases under the influence of unfavorable factors. These include the effect of:

  • chemical carcinogens (especially benzene derivatives);
  • ionizing radiation;
  • some antitumor drugs used to treat cancer of other localizations;
  • chronic viral infection (cytomegalovirus, herpes simplex);
  • unfavorable heredity (if close relatives had leukemia).

In children, the occurrence of blood cancer is often due to genetic abnormalities. In adults, a risk factor is gender (men have the problem more often), age over 50 years, and a long history of smoking.

The provoking factor disrupts the process of blood cell production — erythrocytes, platelets, leukocytes or lymphocytes. Leukocytes degenerate most often.

Healthy cells are produced by bone marrow; this process is continuous. Younger cells are prone to degeneration. If such an anomaly occurs, they divide chaotically, suppress the maturation of normal cells, and gradually replace them. Abnormal cells are carried to all organs with the bloodstream.

Because malignant cells have an abnormal structure, they do not perform their function, as a result organs and systems suffer.

Symptoms

sick person

In the initial stage of the disease, it is rarely possible to suspect a problem. Often it is discovered when a person undergoes a preventive examination or takes tests for other diseases.

As leukemia develops, weakness increases, general tone decreases, and immunity weakens.

A serious health problem can be suspected if:

  • chills, causeless sweating and increased body temperature occur;
  • bruises and hemorrhages appear on the body without apparent cause;
  • rash appears, wounds heal poorly;
  • dizziness worries;
  • joints, bones begin to hurt;
  • noticeable deterioration of memory;
  • insomnia appears or the person becomes drowsy.

During examination, the doctor discovers enlargement of the liver and spleen.

When the disease takes a more severe form, the person loses weight and suffers from bleeding of mucous membranes. They become pale, sometimes the skin acquires a waxy-yellow tint. Bloating appears, pain in the right hypochondrium becomes more frequent.

In children and adults, blood cancer is often accompanied by enlarged lymph nodes.

Diagnostics

diagnostic procedures

Examination of patients with suspected blood cancer is carried out in several stages. In the first stage, the doctor conducts an initial examination and collects anamnesis. The doctor prescribes a complete blood count (with leukocyte formula) and biochemical tests. If their results confirm suspicion of leukemia, the specialist prescribes further diagnostics. It includes:

  • radiological examination — positron emission, magnetic resonance or computed tomography, radiography, ultrasound scanning;
  • sternal puncture (bone marrow collection from the sternum);
  • molecular genetic and cytogenetic studies to identify specific chromosomal damage that helps determine the type of leukemia and its aggressiveness;
  • immunophenotyping — to determine the leukemia subtype and select a treatment method.

In some cases, additional collection and laboratory examination of cerebrospinal fluid for the presence of atypical cells is performed. This information allows selecting the most effective treatment regimen.

Leukemia Treatment Methods

Twenty years ago, leukemia was a death sentence, but today timely treatment of blood cancer in specialized hematological centers allows many patients to overcome the disease. Treatment of many types of blood cancer in Germany is known for its high effectiveness. German doctors use the most advanced methods to treat blood diseases.

An individual protocol is developed for each patient. When creating it, doctors are guided by diagnostic data, the nature of the disease course, and the patient's existing concomitant health problems.

Chemotherapy

photo of cancer cells

This type of treatment for blood diseases is the main one. The use of cytostatic drugs is carried out in several stages:

  1. Intensive induction is carried out to destroy atypical cells (blasts) in the bone marrow and transfer the disease to the remission stage. Induction treatment lasts 1-1.5 months. At the same time, therapy is prescribed that helps preserve the central nervous system. It involves the introduction of drugs into the space between the layers of the spinal cord coverings.
  2. Consolidation — in this phase of treatment, any cells remaining after the induction stage and capable of multiplying and causing the resumption of the cancer process are destroyed.
  3. Stabilization — the longest, final stage of treatment. It is necessary to destroy abnormal cells remaining after the previous two stages. The stabilization phase during treatment in Germany lasts from 2 to 3 years.

Surgical Treatment

Surgical treatment — bone marrow (stem cell) transplantation is used if chemotherapy or other methods did not give effect. Transplantation is also recommended for people with a very high risk of relapse. The difficulty of this stage of treatment lies in finding a donor whose bone marrow would match the patient in all parameters.

Leukemia treatment in German clinics can be performed by bone marrow transplantation from a donor — a close relative or a stranger. During remission, transplantation of the patient's own stem cells is possible.

Innovative Methods

radiation therapy

Blood cancer treatment in Germany is often performed using radiation therapy. To control the achieved results of irradiation, patients are prescribed positron emission tomography. This method is necessary for the most targeted irradiation of affected lymph nodes, metastases and areas of cancer tumors.

Targeted therapy involves the use of special drugs that affect only abnormal cells and destroy them. At the same time, healthy cells and tissues do not suffer. This type of treatment is actively used in Germany, Israel, in leading cancer centers in the USA, South Korea and other countries.

Oncologists prescribe targeted therapy for blood cancer only if the disease has precisely recognizable markers and they respond to the targeted drugs available to doctors.

Immunotherapy for blood cancer treatment in Germany gives very good results. It activates the patient's own immune system, which begins to recognize abnormal cells and destroys them.

Cost

Blood cancer therapy in Germany in some forms of the disease leads to recovery or long-term remission in 90% of cases. Leading multidisciplinary and specialized medical centers in Germany accept not only citizens of their country but also foreign patients.

The cost of treatment is determined by several factors:

  • patient's age;
  • their general condition;
  • stage and severity of the disease;
  • type of pathology.

The cost of treating cancer pathologies in general is the highest among all diseases that can occur in humans. Treatment in Germany is also not cheap. But blood cancer therapy in Germany is a real chance for life. Doctors in this country successfully cope with most types of malignant pathologies of the hematopoietic system in 90% of cases in children under 15 years. The recovery rate of adult cancer patients who have been treated for blood cancer in Germany is also the highest in the world. It reaches (with different forms of pathology) 45-70%.

The exact price of treatment is determined individually. Patients making inquiries to the clinic are provided with a cost calculation for diagnostic procedures and medication interventions. Approximate prices for different stages of treatment (in euros):

  • oncohematologist consultation — from 800;
  • laboratory diagnostics — from 350;
  • chemotherapy (per course) — 3500-5500;
  • autotransplantation — from 100000;
  • transplantation from a related donor — from 200000;
  • transplantation from an unrelated donor — from 250000.

In addition, expenses for preliminary consultations with oncologists, travel expenses, and accommodation in Germany must be taken into account.

Clinics

Blood cancer treatment in Germany is carried out in many public and private clinics of the country. Leading oncohematological centers:

Ludwig Maximilian University Hospital Munich

9.7/10
📍Germany, Munich

29 specialized clinics, 12 specialized institutes, 50 interdisciplinary centers.

After Berlin's Charité, the Munich University Hospital with the Innenstadt and Großhadern campus is the largest maximum care medical complex in Germany.

Munich Municipal Clinics

📍München, Germany

5 separate clinics with common management

A network of multidisciplinary clinics located in five districts of Munich. They provide a high-class range of medical services. The municipal clinics are academic clinics of both Munich universities.
Bogenhausen Clinic
Harlaching Clinic
Neuperlach Clinic
Schwabing Clinic
Thalkirchner Clinic

Technical University Clinic "Rechts der Isar"

9.8/10
📍Germany, Munich

Department of Hematology and Oncology

The Department of Hematology and Oncology offers a full range of diagnostic and therapeutic services in these fields. The highly qualified team of doctors provides patients with effective treatment of all oncological diseases, blood and lymph pathologies (e.g., leukemia, multiple myeloma).

German Oncologists Union Oncology Clinics

📍Germany

OncoUnion Clinics

OncoUnion offers a full range of services for the diagnosis and treatment of malignant oncological diseases, in accordance with international medical standards.

These and other centers have international certificates and licenses. They offer complete examination, consultations with world-class oncohematologists, and effective treatment.

Oncologists in Germany have at their disposal the most advanced treatment methods, the latest equipment and medications. Combined with the highest level of doctor knowledge, this allows most patients who have sought help to live a long, healthy life.

If you or your loved ones have faced trouble and are still thinking about where to treat blood cancer — don't waste time! Contact Doktor München for help with consultation and treatment organization.

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